Patient Education

Health Library

Our Health Library information does not replace the advice of a doctor. Please be advised that this information is made available to assist our patients to learn more about their health. Our providers may not see and/or treat all topics found herein.

Acquired Von Willebrand's Disease

Skip to the navigation

Topic Overview

Acquired von Willebrand's disease is a rare bleeding disorder that might be caused by other medical problems or medicines. It prevents blood from clotting properly. It is rarer than the inherited form of von Willebrand's disease.

Medical problems that might cause acquired von Willebrand's disease include:

Rarely, acquired von Willebrand's disease may also develop in direct association with use of certain medicines. When use is discontinued, signs of the disease also end. These medicines include:

  • Ciprofloxacin.
  • Griseofulvin.
  • Valproic acid.

Symptoms include nosebleeds with no previous history of bleeding abnormalities.

Treatment of acquired von Willebrand's disease includes medicines that help your body have enough von Willebrand clotting factor in the blood. This von Willebrand factor helps your blood clot.

Related Information

References

Other Works Consulted

  • Hillman R, et al. (2011). Platelet dysfunction and von Willebrand disease. In Hematology in Clinical Practice, 5th ed., pp. 384-397. New York: McGraw-Hill.
  • National Heart, Lung, and Blood Institute (2007). The Diagnosis, Evaluation, and Management of von Willebrand Disease. (NIH Publication No. 08-5832). Available online: http://www.nhlbi.nih.gov/guidelines/vwd.
  • Nichols WL (2016). Von Willebrand disease and hemorrhagic abnormalities of platelet and vascular function. In L Goldman, A Shafer, eds., Goldman-Cecil Medicine, 24th ed., vol. 1, pp. 1167-1172. Philadelphia: Saunders.

Credits

ByHealthwise Staff
Primary Medical Reviewer E. Gregory Thompson, MD - Internal Medicine
Adam Husney, MD - Family Medicine
Specialist Medical Reviewer Brian Leber, MDCM, FRCPC - Hematology

Current as ofOctober 9, 2017

This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use and Privacy Policy. Learn how we develop our content.

© 1995-2017 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.